17. Franklin Delano Roosevelt
As Franklin Delano Roosevelt (FDR) victoriously led the US through World War II, he struggled with a more personal battle: polio. Before being elected president, FDR contracted polio in 1921. To help with mobility, he often used a wheelchair or braces that ran the length of his legs. Though FDR’s political opponents frequently cited his polio as evidence for being unfit to run the country, their efforts to thwart him from winning the White House were futile. FDR was one of the US’s most popular presidents, holding a total of four presidential terms.